Safinamide Improved Motor, Non-Motor Symptoms of Parkinson’s Disease in Post Hoc Analysis of Trial Data

Many patients with Parkinson’s disease (PD) experience motor symptoms such as rigidity and tremor and non-motor symptoms such as pain and depression. Safinamide (Xadago), a third-generation monoamine-oxidase B inhibitor, has a dual mechanism of action that appears to address both categories of PD symptoms simultaneously by enhancing dopaminergic transmission while blocking sodium channels to control […]

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Michael J. Fox is fighting hard against Parkinson’s. But it seems like he might be lossing it

Author: Matthys Pretorius Michael Fox continues to work hard amidst his battle with Parkinson’s disease. The Canadian-American actor’s condition seems to be getting worse, as reported by Native Culture. Fox, 56, who rose to prominence in the early 1980’s, began his fight with Parkinson’s disease in the later 90’s. In 1991, he started developing symptoms […]

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Pfizer, pocketing a big tax cut from Trump, will end investment in Alzheimer’s and Parkinson’s research

MICHAEL HILTZIKWith every passing day, it becomes clearer who’s reaping the benefit of the huge tax cut handed over to American corporations by the Republican-dominated Congress in December. Spoiler alert: Not workers or customers, but shareholders, especially the rich ones. (Don’t be fooled by those $1,000 bonuses handed out by a few big companies anxious […]

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Recognizing the Stages of Parkinson’s Disease Progression

By Krisha McCoy Symptoms including tremors, balance issues, and rigid muscles get worse over time in people living with Parkinson’s. Parkinson’s disease is progressive: It gets worse over time. The primary Parkinson’s disease symptoms — tremors, rigid muscles, slow movement (bradykinesia), and difficulty balancing — may be mild at first but will gradually become more intense and debilitating. Stages of […]

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Tech For Parkinson’s: From Apps To Steady Spoons And Walking Sticks

BY, ALICE MELAO. In the UK an estimated 127 thousand people are living with Parkinson’s disease. In the United States, the estimate amounts to more than 1 million. This puts the disease on rank two among the neurodegenerative diseases, second only to Alzheimer’s. Motor symptoms like tremor, rigidity, bradykinesia (slow movement), postural instability (balance problems), […]

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Science Confirms: LRRK2 Gene May Link Crohn’s and Parkinson’s Among Ashkenazi Jews

BY, ALICE MELAO Ashkenazi Jews with Crohn’s disease are more likely to have mutations on the LRRK2 gene — a known cause of inherited Parkinson’s disease  — say researchers with the Icahn School of Medicine at New York’s Mount Sinai Hospital. The study, “Functional variants in the LRRK2 gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease,” appeared in […]

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Administration of Two Proteins Shown to Counteract Neurodegeneration in Parkinson’s Disease

By, Sally Robertson, BSc A combination therapy made up of two neurotrophic factors has been shown to reduce the degenerative effects of Parkinson’s disease, report researchers from the UPV/EHU-University of the Basque Country. The two factors; Vascular Endothelial Growth Factor (VEGF) and Glial Cell-derived Neurotrophic Factor (GDNF), are proteins that play an essential role in nerve cell […]

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THINGS TO REMEMBER ABOUT CBD AND PARKINSON’S DISEASE

Scientists at the University of Louisville School of Medicine in Kentucky have identified a previously unknown molecular target of cannabidiol (CBD), which may have significant therapeutic implications for Parkinson’s Disease (PD). A poster by Zhao-Hui Song and Alyssa S. Laun at the 2017 meeting of the International Cannabinoid Research Society in Montreal disclosed that CBD activates a G-coupled […]

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Parkinson’s disease symptoms: Why a restless night’s sleep could be an EARLY sign

PARKINSON’S disease symptoms include shaking and slow movement. But new research has suggested that a restless night’s sleep could also be an early sign. By LAUREN CLARK Parkinson’s disease is where parts of the brain become progressively damaged over a number of years. It affects 127,000 people in the UK, and rates of the condition are […]

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